Immune Age, Cardiovascular Disease, And Anti-Viral Immunity
As we get older, our immune system also ages, a process sometimes called “immune aging” or “immunosenescence.” This doesn’t just mean we’re more likely to catch a cold; it has profound effects on our overall health. One major impact is on our cardiovascular system, which includes our heart and blood vessels. The aging immune system can lead to a state of chronic, low-grade inflammation throughout the body, known as “inflammaging.” This persistent inflammation is a key factor in the development and worsening of cardiovascular diseases, particularly atherosclerosis, where plaque builds up in the arteries. Simultaneously, this aged immune system becomes less effective at recognizing and fighting off viral infections, making older individuals more susceptible to severe illness from viruses. What’s particularly interesting is that these two issues—cardiovascular disease and weakened anti-viral immunity—are not separate. They are interconnected. The very act of fighting off a viral infection can sometimes trigger an overactive immune response that, while trying to eliminate the virus, can also inadvertently damage blood vessels and worsen existing cardiovascular conditions. Conversely, existing cardiovascular disease can also negatively impact the immune system, making it even harder to mount an effective defense against viruses. Understanding these shared pathways is crucial for developing new strategies to promote healthy aging and protect against both heart disease and infectious illnesses.
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