Immune Age, Cardiovascular Disease, And Anti-Viral Immunity
As we age, our immune system undergoes significant changes, a process often referred to as “immune aging.” This doesn’t just mean our bodies become less effective at fighting off infections; it also involves a persistent, low-grade inflammation throughout the body, termed “inflammaging.” These age-related shifts in our immune defenses have a dual impact on our health. Firstly, immune aging weakens our ability to mount strong, protective responses against viruses, making older individuals more vulnerable to severe infections like the flu or shingles. Secondly, the chronic inflammation associated with aging actively contributes to the development and progression of cardiovascular diseases, such as hardening of the arteries. Interestingly, these two health challenges are not isolated. The effort to fight off a viral infection can actually put additional stress on the immune system, leading to a kind of “exhaustion” that can worsen existing heart conditions. Conversely, cardiovascular diseases can alter how our immune cells function, making them less effective at defending against pathogens and potentially fueling further inflammation in blood vessels. Understanding these complex interactions is crucial for developing strategies to promote healthier aging and protect against both infectious diseases and heart conditions.
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