Research On The Antiaging Activity Of Licorice Water Extract In Aging Mice Via Antioxidation, Neuronal Protection, Gut Microbiota Restoration, And Pi3K/AKT/Mtor Modulation
Aging is a complex process that affects our bodies in many ways, leading to issues like oxidative stress, declining brain function, and changes in our gut bacteria. Scientists are constantly looking for natural compounds that might help combat these effects.
One such compound, derived from a widely used traditional herb, has shown promising anti-aging properties in recent research. This study explored how an extract from this herb could influence the aging process in mice.
The findings revealed several key benefits. Firstly, the extract boosted the body’s natural defenses against harmful molecules, acting as an antioxidant to protect cells from damage. Secondly, it offered protection to brain cells, which in turn improved cognitive abilities like learning and memory. Thirdly, it helped restore a healthy balance of gut microbiota, the beneficial bacteria living in our intestines, which are crucial for overall health and can be disrupted during aging.
Furthermore, the research delved into the underlying mechanisms, discovering that the extract influenced a critical cellular pathway known as PI3K/AKT/mTOR. This pathway acts like a master switch, regulating various cellular processes including growth, survival, and metabolism, all of which play a significant role in aging. By modulating this pathway, the extract appears to contribute to its anti-aging effects.
These results suggest that this traditional herb could be a promising candidate for developing new strategies to promote healthy aging by addressing multiple aspects of age-related decline.
Source: link to paper