Unlocking The Anti-Aging Potential Of Lycium Barbarum Polysaccharides: Structure-Activity Insights, Mechanisms, And Future Therapeutics

Therapeutic
Aging Pathway
Lycium barbarum polysaccharides demonstrate significant potential in combating aging and age-related diseases by enhancing immunity, modulating gut microbiota, and exhibiting strong antioxidant and anti-inflammatory properties.
Author

Gemini

Published

January 27, 2026

Goji berries, a revered superfood, contain powerful natural compounds known as polysaccharides that are drawing significant scientific interest for their anti-aging capabilities. Recent research sheds light on how these compounds, often called LBPs, work within the body. They appear to boost our immune system, help maintain a healthy balance of gut bacteria, and reduce widespread inflammation caused by oxidative stress. Oxidative stress occurs when there’s an imbalance between harmful free radicals and the body’s ability to neutralize them, leading to cellular damage and contributing to aging and various diseases. These beneficial molecules act as potent antioxidants, directly scavenging these damaging free radicals and protecting cells. Beyond general anti-aging effects, studies indicate these compounds may offer neuroprotection, potentially improving cognitive functions like learning and memory, and alleviating pathological changes in brain tissue by regulating specific signaling pathways and enhancing synaptic protein expression. They also show promise in reducing neuroinflammation by inhibiting the activity of certain immune cells and inflammatory pathways. The potential applications of these remarkable compounds are vast, ranging from their inclusion in functional foods and medicines to animal feed and even skincare products. While the findings are promising, ongoing research is crucial to fully understand their intricate structures and optimize their therapeutic use.


Source: link to paper