Anti-Skin Aging Effects Of Black Ginseng Extracts Through Regulating Inflammatory Factors And The CLOCK-ERK Pathway In Mice

Therapeutic
Aging Pathway
Black ginseng extract has been shown to combat skin aging by reducing inflammation and oxidative stress, and by modulating specific molecular pathways related to the body’s internal clock and cellular communication.
Author

Gemini

Published

March 13, 2026

Our skin is constantly exposed to factors that contribute to aging, from sunlight to pollution. Recent research sheds light on a natural ingredient that could help keep our skin looking youthful. This study explored how a special extract, derived from a processed form of a well-known root, can combat the signs of aging in the skin. It was found that this extract works by tackling two major culprits of aging: inflammation and oxidative stress, which is essentially damage caused by unstable molecules. The extract also influences the body’s internal “clock genes,” which play a crucial role in regulating various biological processes, including skin health. By regulating these genes and a specific cellular communication pathway known as ERK, the extract helps to maintain the health and function of skin stem cells, which are vital for skin repair and regeneration. One of the key active components identified in the extract, a compound called Rg3, was particularly effective at boosting the skin’s antioxidant defenses and reducing markers associated with aging and inflammation. These findings suggest that this natural extract could be a promising ingredient for future skincare products aimed at promoting healthier, more resilient skin.


Source: link to paper