Micro- And Nanoplastics Exposure Across The Lifespan: One Health Implications For Aging And Longevity
Invisible threats are all around us, even in the air we breathe and the food we eat. We’re talking about tiny plastic particles, known as micro- and nanoplastics, which are now recognized as widespread environmental contaminants. These minuscule fragments enter our bodies mainly through what we eat and drink, and even the air we inhale.
Once inside, these particles don’t just pass through; they can accumulate in vital organs like the brain, lungs, liver, and gut. Research indicates that these plastic invaders can trigger a cascade of cellular responses that are strikingly similar to the processes of aging. This includes increased oxidative stress, which is like rust forming in our cells, and chronic inflammation, a persistent immune response that can damage tissues. They can also disrupt our cells’ energy factories, called mitochondria, and lead to cellular senescence, where cells stop dividing and can contribute to aging.
These cellular disturbances are not isolated; they are linked to problems in major bodily systems, including our heart and blood vessels, nervous system, digestive tract, and immune defenses. What’s more, these plastic particles can act as tiny carriers for other harmful chemicals and pollutants, potentially magnifying their negative health effects.
Understanding this challenge requires a “One Health” approach, recognizing that the health of humans, animals, and our shared environment are deeply interconnected. While we’re learning more about these microscopic threats, there’s still a critical need for more research, especially to understand their long-term effects on human health, particularly in older populations.
Source: link to paper