From The Lab To Lifestyle: Epigenetic Clocks In Personalized Aging And Health
Our bodies age at different rates, and scientists are developing tools to measure this “biological age” more accurately than just counting years. These tools, often called biological clocks, look at tiny chemical tags on our DNA, specifically at places called CpG sites, in a process known as DNA methylation. DNA methylation refers to chemical modifications on our DNA that can turn genes on or off, and these patterns change as we age. These changes can reveal how quickly our bodies are aging at a cellular level.
Initially, these clocks were good at predicting a person’s actual age. However, newer versions have become much more sophisticated, now able to predict risks for various diseases and even how fast someone is truly aging. This is a big step because it offers a more personalized view of health than just looking at a birthdate.
While these advanced biological clocks are powerful, they often rely on complex and expensive technologies, making them difficult to use widely in clinics or for individual health management. There’s a growing demand for simpler, more affordable versions that can still provide accurate insights. For example, some promising new models focus on just a few key DNA tags, making the tests easier and cheaper to perform. The ultimate goal is to make these insights accessible to everyone, allowing for truly personalized strategies to promote healthy aging and prevent age-related diseases.
Source: link to paper