Effects Of Nutritional Interventions On Biomarkers Of Cellular Senescence In Humans: A Systematic Review
As we age, our bodies accumulate “zombie cells,” also known as senescent cells. These cells stop dividing but don’t die off, instead lingering and releasing harmful substances that can contribute to aging and age-related diseases. Scientists are exploring ways to target these cells to promote healthier aging.
Recent research has systematically reviewed the impact of various dietary ingredients on these cellular aging markers. The findings suggest some exciting possibilities from animal studies: compounds like resveratrol (found in grapes and red wine), vitamin E, and soy protein isolate have shown positive effects in reducing the presence of these “zombie cells” in animal models.
However, when it comes to human studies, the picture is less clear. The review highlighted that there are very few human trials investigating the effects of dietary interventions on cellular aging. For instance, one ingredient, ginsenoside Rg1, did not demonstrate a positive effect on reducing cellular aging in human muscle tissue after exercise.
This means that while the animal research offers promising clues, we need significantly more studies in humans to understand whether these dietary components can truly help us combat cellular aging and promote a healthier lifespan.
Source: link to paper