Rethinking Aging Biomarkers In HIV: From Measures To Meaning
Even with effective treatments, individuals living with HIV often experience age-related health issues earlier and more severely than the general population. This accelerated aging isn’t due to a single factor but rather a complex interplay of various bodily systems, including the immune system and metabolism, which become dysregulated over time. To better understand and address this, scientists are exploring “biomarkers,” which are measurable indicators of biological processes, like specific molecules in the blood or changes in body functions. However, no single biomarker can fully capture the intricate process of aging in people with HIV. The key lies in using a combination of these indicators, integrating various biological and functional measurements. By combining these “multimodal” approaches with advanced tools like artificial intelligence and machine learning, researchers aim to improve how we predict health risks, monitor the effectiveness of treatments, and develop new interventions to promote healthier aging for people living with HIV.
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